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Impact of Dietary Supplementation of Different Levels of Black Seeds (Nigella sativa L.) On Production Performance, Mortality and Immunity of Broiler Chickens
Abstract
Background and Objective: Generous use of antibiotics in the broiler diets is a common practice in the broiler industry for promoting growth and enhance the immune responsiveness. Subsequently, resulted in occurrence of resistance amongst pathogens and potential for residuals in broiler chicken body tissue. The current study was carried out to evaluate the impact of various levels of black cumin seeds (BCS) dietary supplementation on growth performance, mortality and immune response of broiler chickens. Materials and Methods: Two-hundred fifty-five, one-day old Cobb 500 broiler chicks were randomly assigned into three treatment batteries with five replicates of 17 chicks each. Three levels of black cumin seeds (0, 1 and 3%) were fed in the diets of the test broilers, in which the group with 0% served as a control. Results: Diets supplemented with black cumin seeds significantly (p<0.05) improved the growth performance parameters such as body weight, body weight gain, feed consumption, feed efficiency and mortality percent as compared to the control group. In addition, diets supplemented with black cumin significantly (p<0.05) increased the bursa and thymus weights and improved antibody production, as well as the immune-responsiveness of birds. Conclusion: Dietary supplement of black cumin seeds at the level of 1 and 3% may improve production performance and potential for improving immune-responsiveness of broiler chicken.
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Black cumin seeds, broiler growth, immune-responsiveness, lymphoid organs, natural additivesArticle Metrics
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Abdullah , F. K., Al-Nasser, A. Y., Al-Saffar, A., Omar, A. E., & Ragheb, G. (2019). Impact of Dietary Supplementation of Different Levels of Black Seeds (Nigella sativa L.) On Production Performance, Mortality and Immunity of Broiler Chickens. International Journal of Poultry Science, 18(10), 467–474. https://doi.org/10.3923/ijps.2019.467.474
References
1.
Aydin, R., M. Karaman, T. Cicek and H. Yardibi, 2008. Black cumin (Nigella sativa L.) supplementation into the diet of the laying hen positively influences egg yield parameters, shell quality and decreases egg cholesterol. Poult. Sci., 87: 2590-2595.
2.
Kumar, P., A.K. Patra, G.P. Mandal, I. Samanta and S. Pradhan, 2017. Effect of black cumin seeds on growth performance, nutrient utilization, immunity, gut health and nitrogen excretion in broiler chickens. J. Sci. Food Agric., 97: 3742-3751.
3.
Schwarz, S., C. Kehrenberg and T.R. Walsh, 2001. Use of antimicrobial agents in veterinary medicine and food animal production. Int. J. Antimicrob. Agents, 17: 431-437.
4.
European Council Directive, 2007. Council Directive 2007/43/EC laying down minimum rules for the protection of chickens kept for meat production. Official J. Eur. Commun., L182: 19-28.
5.
Toghyani, M., M. Toghyani, A. Gheisari, G. Ghalamkari and M. Mohammadrezaei, 2010. Growth performance, serum biochemistry and blood hematology of broiler chicks fed different levels of black seed (Nigella sativa) and peppermint (Mentha piperita). Livest. Sci., 129: 173-178.
6.
Mahmoud, M.R., H.S. El-Abhar and S. Saleh, 2002. The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice. J. Ethnopharmacol., 79: 1-11.
7.
Al-Hader, A., M. Aqel and Z. Hasan, 1993. Hypoglycemic effects of the volatile oil of Nigella sativa seeds. Int. J. Pharmacol., 31: 96-100.
8.
Zaoui, A., Y. Cherrah, M.A. Lacaille-Dubois, A. Settaf, H. Amarouch and M. Hassar, 2000. Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat. Therapie, 55: 379-382, (In French).
9.
Al-Beitawi, N.A., S.S. El-Ghousein and M.Z. Athamneh, 2010. Effect of adding crushed Pimpinella anisum, Nigella sativa seeds and Thymus vulgaris mixture to antibiotics-free rations of vaccinated and non-vaccinated male broilers on growth performance, antibody titer and haematological profile. Ital. J. Anim. Sci., Vol. 9.
10.
Babayan, V.K., D. Koottungal and G.A. Halaby, 1978. Proximate analysis, fatty acid and amino acid composition of Nigella sativa L. seeds. J. Food Sci., 43: 1314-1315.
11.
Al-Beitawi, N.A., S.S. El-Ghousein and A.H. Nofal, 2009. Replacing bacitracin methylene disalicylate by crushed Nigella sativa seeds in broiler rations and its effects on growth, blood constituents and immunity. Livestock Sci., 125: 304-307.
12.
Al-Mufarrej, S.I., 2014. Immune-responsiveness and performance of broiler chickens fed black cumin (Nigella sativa L.) powder. J. Saudi Soc. Agric. Sci., 13: 75-80.
13.
NRC., 1994. Nutrients Requirements of Poultry. 9th Rev. Edn., National Academic Press, Washington, USA., ISBN-13: 9780309596329, Pages: 156.
14.
Wagner, D.D., R.D. Furrow and B.D. Bradly, 1983. Sub chronic toxicity of growth promoters in broiler chickens. Vet. Path., 20: 253-359.
15.
Mashaly, M.M., G.L. Hendricks, M.A. Kalama, A.E. Gehad, A.O. Abbas and P.H. Patterson, 2004. Effect of heat stress on production parameters and immune responses of commercial laying hens. Poult. Sci., 83: 889-894.
16.
SAS., 1999. SAS User's Guide Version 6.04. 4th Edn., SAS Institute Inc., Cary, NC.
17.
Rahman, M.M. and S.J. Kim, 2016. Effects of dietary Nigella sativa seed supplementation on broiler productive performance, oxidative status and qualitative characteristics of thighs meat. Ital. J. Anim. Sci., 15: 241-247.
18.
Guler, T., B. Dalkilic, O.N. Ertas and M. Ciftci, 2006. The effect of dietary black cumin seeds (Nigella sativa L.) on the performance of broilers. Asian-Aust. J. Anim. Sci., 19: 425-430.
19.
El Bagir, N.M., A.Y. Hama, R.M. Hamed, A.G. Abd El Rahim and A.C. Beynen, 2006. Lipid composition of egg yolk and serum in laying hens fed diets containing black cumin (Nigella sativa). Int. J. Poult. Sci., 5: 574-578.
20.
Mahmood, S., M.M.U. Hassan, M. Alam and F. Ahmad, 2009. Comparative efficacy of Nigella sativa and Allium sativum as growth promoters in broilers. Int. J. Agric. Biol., 11: 775-778.
21.
Abudabos, A.M. and S.I. Al-Mufarrej, 2014. Effects of organic acid supplementation on antioxidant capacity and immune responses of broilers challenged orally with Salmonella enteric subsp. enterica Typhimurium. S. Afr. J. Anim. Sci., 44: 343-349.
22.
Akhtar, M.S., Z. Nasir and A.R. Abid, 2003. Effect of feeding powdered Nigella sativa L. seeds on poultry egg production and their suitability for human consumption. Veterinarski Arhiv., 73: 181-190.
23.
Majeed, L.H.A., K.A. Abdelati, N.M. El-Bagir, A. Alhaidary, H.E. Mohamed and A.C. Beynen, 2010. Performance of broiler chickens fed diets containing low inclusion levels of black cumin seed. J. Anim. Vet. Adv., 9: 2725-2728.
24.
Khalaji, S., M. Zaghari, K.H. Hatami, S. Hedari-Dastjerdi, L. Lotfi and H. Nazarian, 2011. Black cumin seeds, Artemisia leaves (Artemisia sieberi) and Camellia L. plant extract as phytogenic products in broiler diets and their effects on performance, blood constituents, immunity and cecal microbial population. Poult. Sci., 90: 2500-2510.
25.
Erener, G., A. Altop, N. Ocak, H.M. Aksoy, S. Cankaya and E. Ozturk, 2010. Influence of black cumin seed (Nigella sativa L.) and seed extract on broilers performance and total coliform bacteria count. Asian J. Anim. Vet. Adv., 5: 128-135.
26.
Abu-Dieyeh, Z.H.M. and M.S. Abu-Darwish, 2008. Effect of feeding powdered black cumin seeds (Nigella sativa L.) on growth performance of 4-8 week-old broilers. J. Anim. Vet. Adv., 3: 286-290.
27.
Soliman, A.Z.M., A.A. Ghazalah, S.H. El-Samra, A.M. Atta and Z.M.A. Abdo, 1999. The synergistic effect of either black seed or garlic with fat on broiler performance and immunity. Proceedings of the 7th Scientific Conference on Animal Nutrition (ruminants, poultry and fish), October 19-21, 1999, El-Arish, Egypt, pp: 603-620.
28.
Oyen, L.P.A. and N.X. Dung, 1999. Essential-oil Plants. Backhuys Publishhers, Leiden, Pages: 277.
29.
Hay, R.K.M. and K.M. Waterman, 1993. Volatile Oil Crops: Their Biology Biochemistry and Production. Longman Science and Technology, USA., ISBN: 9780582005570, Pages: 185.
30.
Azeem, T., Zaib-Ur-Rehman, S. Umar, M. Asif, M. Arif and A. Rahman, 2014. Effect of Nigella sativa on poultry health and production: A review. Sci. Lett., 2: 76-82.
31.
Al-Harthi, M.A., 2004. Efficiency of utilizing some spices and herbs with or without antibiotic supplementation on growth performance and carcass characteristics of broiler chicks. Egypt. Poult. Sci. J., 24: 869-899.
32.
Khan, S.H., J. Ansari, A.U. Haq and G. Abbas, 2012. Black cumin seeds as phytogenic product in broiler diets and its effects on performance, blood constituents, immunity and caecal microbial population. Ital. J. Anim. Sci., 11: 438-444.
33.
Agarwal, R., M.D. Kharya and R. Shrivastava, 1979. Pharmacological studies of essential oil and unsaponifiable matter of seeds of Nigella sativa. Ind. J. Pharmacol. Sci., 41: 248-248.
34.
Hanafy, M.S.M. and M.E. Hatem, 1991. Studies on the antimicrobial activity of Nigella sativa seed (black cumin). J. Ethnopharmacol., 34: 275-278.
35.
Gilani, A.H., Q. Jabeen and M.A.U. Khan, 2004. A review of medicinal uses and pharmacological activities of Nigella sativa. Pak. J. Biol. Sci., 7: 441-451.
36.
Hedaya, S.A., 1995. Effect of Nigella sativa (black seeds) extract on some haematological and biochemical parameters in rats. Alex. J. Vet. Sci., 11: 95-99.
37.
Shewita, R.S. and A.E. Taha, 2011. Effect of dietary supplementation of different levels of black seeds (Nigella sativa L.) on growth, performance, immunological, hematological and carcass parameters of broiler chicks. World Acad. Sci. Eng. Tech., 77: 788-794.
38.
Tollba, A.A.H. and M.S.H. Hassan, 2003. Using some natural additives to improve physiological and productive performance of broiler chicks under high temperature conditions 2- black cumin (Nigella sativa) or garlic (Allium sativum). Egypt. Poul. Sci., 23: 327-340.
39.
El-Deek, A.A., S.M. Hamdy, Y.A. Attia and M.M. Khalifah, 2009. Nigella sativa seed oil meal as a source of plant protein in broiler diets. Egypt. Poult. Sci., 29: 39-52.
40.
Glick, B., T.S. Chang and R.G. Jaap, 1956. The bursa of fabricius and antibody production. Poult. Sci., 35: 224-225.
41.
Todar, K., 2005. Immune defense against microbial pathogen. Online Textbook of Bacteriology. http://www.textbookofbacteriology.net/.
42.
Karmous, A.M., K.M.B. Naser, L. Abuzaid and A. Asheg, 2016. Duration of feeding black seed (Nigella sativa) to broiler chicks and its effect on immune response, cholesterol and gut microflora. Res. J. Pharm. Biol. Chem. Sci., 7: 183-187.
43.
Durrani, F.R., N. Chand, K. Zaka, A. Sultan, F.M. Khattak and Z. Durrani, 2007. Effect of different levels of feed added black seed (Nigella sativa L.) on the performance of broiler chicks. Pak. J. Biol. Sci., 10: 4164-4167.
