Influenza A Viruses in Poultry: A Condensed Review


Authors

  • Sigfrido Burgos Department of Agriculture and Consumer Protection, Animal Production and Health Division, Livestock Information, Sector Analysis and Policy Branch (AGAL), Pro-Poor Livestock Policy Initiative (PPLPI), Food and Agriculture Organization of the United Nations (FAO), Viale delle Terme di Caracalla, 00153, Rome, Italy
  • Sergio A. Burgos Department of Animal and Poultry Science, University of Guelph, Guelph, ON, N1G 2W1, Canada

DOI:

https://doi.org/10.3923/ijps.2007.705.708

Keywords:

Highly pathogenic avian influenza, HPAI H5N1, influenza A virus, poultry

Abstract

Influenza A viruses are comprised of 8 negative-sense RNA segments coding 11 proteins; divided into low and high pathogenicity. They use recombination, deletions and insertions to escape immune system detection. Its epidemiology is defined by interactions between the host, agent and environment. Wild birds are their natural reservoirs; they replicate in the intestinal tract, shed in faeces and transmitted by faecal-oral transmission. They attach to host cells by binding to sialosaccharides on the host cell surface, predominantly to type II pneumocytes, alveolar macrophages and nonciliated cuboidal epithelial cells in terminal bronchioles. High mortality rates of 61% in humans and 90-100% in poultry are seen.

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Published

2007-09-15

Issue

Section

Research Article

How to Cite

Burgos, S., & Burgos, S. A. (2007). Influenza A Viruses in Poultry: A Condensed Review. International Journal of Poultry Science, 6(10), 705–708. https://doi.org/10.3923/ijps.2007.705.708

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