Roles of Fructooligosaccharides and Phytase in Broiler Chickens: Review
DOI:
https://doi.org/10.3923/ijps.2017.16.22Keywords:
Broiler, enzymes, fructooligosaccharides, phytase, prebioticsAbstract
Supplementing prebiotics and enzymes into poultry diets are among the most effective strategies in order to improve nutrient utilization, growth performance, intestinal development, immune system, intestinal microbiome and gut health. Fructooligosaccharides (FOS) is one of the most common prebiotics used in poultry. It has been reported that dietary FOS supplementation in broilers improved body weight gain, feed conversion and carcass yield. It could also enhance intestinal development, improve immune responses and increase short chain fatty acid fermentation of the broilers. Furthermore, Salmonella infection has been reduced by FOS supplementation into broiler diets. Phytase supplementation is one of the successful enzyme application in poultry. Phytase supplementation has increased body weight gain, Ca and P utilization and bone development in broilers. The combination of prebiotics and phytase, based on the modes of action of each component has shown potential benefit in poultry. Prebiotics is capable of increasing gut fermentation, producing short chain fatty acid and reducing gut pH. It has been hypothesized that prebiotics supplementation could create an acidic environment, which is favorable for phytase, increasing phytase activity and P utilization in the intestine. Therefore, the combination of prebiotics and enzyme could be a potential strategy to improve gut health and nutrient utilization in poultry.
References
Gaggia, F., P. Mattarelli and B. Biavati, 2010. Probiotics and prebiotics in animal feeding for safe food production. Int. J. Food. Microbiol., 141: S15-S28.
Gibson, G.R. and M.B. Roberfroid, 1995. Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics. J. Nutr., 125: 1401-1412.
Nahm, K.H., 2002. Efficient feed nutrient utilization to reduce pollutants in poultry and swine manure. Crit. Rev. Environ. Sci. Technol., 32: 1-16.
Naves, L.D.P., A.D. Correa, A.G. Bertechini, E.M. Gomide and C.D. Santos, 2012. Effect of ph and temperature on the activity of phytase products used in broiler nutrition. Rev. Bras. Cienc. Avic., 14: 181-185.
Selle, P.H. and V. Ravindran, 2007. Microbial phytase in poultry nutrition. Anim. Feed Sci. Technol., 135: 1-41.
Dankowiakowska, A., I. Kozlowska and M. Bednarczyk, 2013. Probiotics, prebiotics and snybiotics in poultry-mode of action, limitation and achievements. J. Central Eur. Agric., 14: 467-478.
Janardhana, V., M.M. Broadway, M.P. Bruce, J.W. Lowenthal, M.S. Geier, R.J. Hughes and A.G.D. Bean, 2009. Prebiotics modulate immune responses in the gut-associated lymphoid tissue of chickens. J. Nutr., 139: 1404-1409.
Maenz, D.D. and H.L. Classen, 1998. Phytase activity in the small intestinal brush border membrane of the chicken. Poult. Sci., 77: 557-563.
Wyss, M., R. Brugger, A. Kronenberger, R. Remy and R. Fimbel et al., 1999. Biochemical characterization of fungal phytases (myo-inositol hexakisphosphate phosphohydrolases): Catalytic properties. Applied Environ. Microbiol., 65: 367-373.
Boling, S.D., M.W. Douglas, M.L. Johnson, X. Wang, C.M. Parsons, K.W. Koelkebeck and R.A. Zimmermant, 2000. The effects of dietary available phosphorus levels and phytase on performance of young and older laying hens. Poult. Sci., 79: 224-230.
Coppedge, J., J. Klein, B. Brown, B. Ratliff, F. Ruch and J.T. Lee, 2011. Effects of co-administration of phytase and nspase on broiler performance and bone ash. Int. J. Poult. Sci., 10: 933-939.
Powell, S., T.D. Bidner and L.L. Southern, 2011. Phytase supplementation improved growth performance and bone characteristics in broilers fed varying levels of dietary calcium. Poult. Sci., 90: 604-608.
Shang, Y., A. Rogiewicz, R. Patterson, B.A. Slominski and W.K. Kim, 2015. The effect of phytase and fructooligosaccharide supplementation on growth performance, bone quality and phosphorus utilization in broiler chickens. Poult. Sci., 94: 955-964.
Cummings, J.H., G.T. Macfarlane and H.N. Englyst, 2001. Prebiotic digestion and fermentation. Am. J. Clin. Nutr., 73: 415S-420S.
Boguslawska-Tryk, M., A. Piotrowska and K. Burlikowska, 2012. Dietary fructans and their potential beneficial influence on health and performance parametrs in broiler chickens. J. Central Eur. Agric., 13: 272-291.
Hidaka, H. and M. Hirayama, 1991. Useful characteristics and commercial applications of fructo-oligosaccharides. Biochem. Soc. Trans., 19: 561-565.
Swiatkiewicz, S., J. Koreleski and A. Arczewska-Wlosek, 2011. Effect of inulin and oligofructose on performance and bone characteristics of broiler chickens fed on diets with different concentrations of calcium and phosphorus. Br. Poult. Sci., 52: 483-491.
Nyman, M., 2002. Fermentation and bulking capacity of indigestible carbohydrates: The case of inulin and oligofructose. Br. J. Nutr., 87: S163-S168.
Scholz-Ahrens, K.E., G. Schaafsma, E.G.H.M. van den Heuvel and J. Schrezenmeir, 2001. Effects of prebiotics on mineral metabolism. Am. J. Clin. Nutr., 73: 459s-464s.
Williams, J., S. Mallet, M. Leconte, M. Lessire and I. Gabriel, 2008. The effects of fructo-oligosaccharides or whole wheat on the performance and digestive tract of broiler chickens. Br. Poult. Sci., 49: 329-339.
Yusrizal and T.C. Chen, 2003. Effect of adding chicory fructans in feed on fecal and intestinal microflora and excreta volatile ammonia. Int. J. Poult. Sci., 2: 188-194.
Bailey, J.S., L.C. Blankenship and N.A. Cox, 1991. Effect of fructooligosaccharide on Salmonella colonization of the chicken intestine. Poult. Sci., 70: 2433-2438.
Xu, Z.R., C.H. Hu, M.S. Xia, X.A. Zhan and M.Q. Wang, 2003. Effects of dietary fructooligosaccharide on digestive enzyme activities, intestinal microflora and morphology of male broilers. Poult. Sci., 82: 1030-1036.
Yang, Y., P.A. Iji and M. Choct, 2009. Dietary modulation of gut microflora in broiler chickens: A review of the role of six kinds of alternatives to in-feed antibiotics. World's Poult. Sci. J., 65: 97-114.
Fox, J.G., 2002. The non-h pylori helicobacters: Their expanding role in gastrointestinal and systemic diseases. Gut, 50: 273-283.
Shang, Y., A. Regassa, J.H. Kim and W.K. Kim, 2015. The effect of dietary fructooligosaccharide supplementation on growth performance, intestinal morphology and immune responses in broiler chickens challenged with Salmonella enteritidis lipopolysaccharides. Poult. Sci., 94: 2887-2897.
Flickinger, E.A., J. van Loo and G.C. Fahey, 2003. Nutritional responses to the presence of inulin and oligofructose in the diets of domesticated animals: A review. Crit. Rev. Food Sci. Nutr., 43: 19-60.
Kim, G.B., Y.M. Seo, C.H. Kim and I.K. Paik, 2011. Effect of dietary prebiotic supplementation on the performance, intestinal microflora and immune response of broilers. Poult Sci., 90: 75-82.
Yang, Y., P.A. Iji, A. Kocher, L.L. Mikkelsen and M. Choct, 2008. Effects of mannanoligosaccharide and fructooligosaccharide on the response of broilers to pathogenic Escherichia coli challenge. Br. Poult. Sci., 49: 550-559.
Emami, N.K., A. Samie, H.R. Rahmani and C.A. Ruiz-Feria, 2012. The effect of peppermint essential oil and fructooligosaccharides, as alternatives to virginiamycin, on growth performance, digestibility, gut morphology and immune response of male broilers. Anim. Feed Sci. Technol., 175: 57-64.
Chambers, J.R. and J. Gong, 2011. The intestinal microbiota and its modulation for Salmonella control in chickens. Food Res. Int., 44: 3149-3159.
Van Immerseel, F., L. de Zutter, K. Houf, F. Pasmans, F. Haesebrouck and R. Ducatelle, 2009. Strategies to control Salmonella in the broiler production chain. World's Poult. Sci. J., 65: 367-392.
Mullaney, E.J. and A.H.J. Ullah, 2003. The term phytase comprises several different classes of enzymes. Biochem. Biophys. Res. Commun., 312: 179-184.
Mittal, A., G. Singh, V. Goyal, A. Yadav, K.R. Aneja, S.K. Gautam and N.K. Aggarwal, 2011. Isolation and biochemical characterization of acido-thermophilic extracellular phytase producing bacterial strain for potential application in poultry feed. Jundishapur J. Microbiol., 4: 273-282.
Slominski, B.A., 2011. Recent advances in research on enzymes for poultry diets. Poult. Sci., 90: 2013-2023.
Woyengo, T.A., B.A. Slominski and R.O. Jones, 2010. Growth performance and nutrient utilization of broiler chickens fed diets supplemented with phytase alone or in combination with citric acid and multicarbohydrase. Poult. Sci., 89: 2221-2229.
Knowlton, K.F., J.S. Radcliffe, C.L. Novak and D.A. Emmerson, 2004. Animal management to reduce phosphorus losses to the environment. J. Anim. Sci., 82: E173-E195.
Simons, P.C.M., H.A.J. Versteegh, A.W. Jongbloed, P.A. Kemme and P. Slump et al., 1990. Improvement of phosphorus availability by microbial phytase in broilers and pigs. Br. J. Nutr., 64: 525-540.
El-Sherbiny, A.E., H.M.A. Hassan, M.O. Abd-Elsamee, A. Samy and M.A. Mohamed, 2010. Performance, bone parameters and phosphorus excretion of broilers fed low phosphorus diets supplemented with phytase from 23 to 40 days of age. Int. J. Poult. Sci., 9: 972-977.
Angel, R., W.W. Saylor, A.D. Mitchell, W. Powers and T.J. Applegate, 2006. Effect of dietary phosphorus, phytase and 25-hydroxycholecalciferol on broiler chicken bone mineralization, litter phosphorus and processing yields. Poult. Sci., 85: 1200-1211.
Woyengo, T.A., W. Guenter, J.S. Sands, C.M. Nyachoti and M.A. Mirza, 2008. Nutrient utilisation and performance responses of broilers fed a wheat-based diet supplemented with phytase and xylanase alone or in combination. Anim. Feed Sci. Technol., 146: 113-123.
Powell, S., S. Johnston, L. Gaston and L.L. Southern, 2008. The effect of dietary phosphorus level and phytase supplementation on growth performance, bone-breaking strength and litter phosphorus concentration in broilers. Poult. Sci., 87: 949-957.
Chung, T.K., S.M. Rutherfurd, D.V. Thomas and P.J. Moughan, 2013. Effect of two microbial phytases on mineral availability and retention and bone mineral density in low-phosphorus diets for broilers. Br. Poult. Sci., 54: 362-373.
Wang, Y., T. Zeng, S.E. Wang, W. Wang, Q. Wang and H.X. Yu, 2010. Fructo-oligosaccharides enhance the mineral absorption and counteract the adverse effects of phytic acid in mice. Nutrition, 26: 305-311.
Lopez, H.W., C. Coudray, M.A. Levrat-Verny, C. Feillet-Coudray, C. Demigne and C. Remesy, 2000. Fructooligosaccharides enhance mineral apparent absorption and counteract the deleterious effects of phytic acid on mineral homeostasis in rats. J. Nutr. Biochem., 11: 500-508.
Selle, P.H., A.J. Cowieson and V. Ravindran, 2009. Consequences of calcium interactions with phytate and phytase for poultry and pigs. Livest. Sci., 124: 126-141.
Downloads
Published
Issue
Section
License
Copyright (c) 2017 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.