Roles of Curcumin and Monochromatic Light in Optimizing Liver Function to Support Egg Yolk Biosynthesis in Magelang Ducks
DOI:
https://doi.org/10.3923/ijps.2016.414.424Keywords:
Curcumin, diameter follicle, egg-yolk biosynthesis, estradiol, hepatocyte, monochromatic light, sexually mature of magelang duck, vitellogeninAbstract
Backgroud: The biosynthesis of vitellogenin as an egg-yolk precursor in oviparous animals is occurred in the liver cells. The vitellogenin synthetic capacity of hepatocyte is under the control of estrogen that its secretion increase when the oviparous animals reach sexual maturity. This experiment was designed to study the uses of curcumin and artificial monochromatic light on liver performance to improve vitellogenin synthesis to support egg production during laying period. Materials and Methods: One hundred and ninety two female magelang ducks were assigned into a completely randomized design with a 4×4 factorial arrangement. The first factor was dose of curcumin supplementation consisted of 4 levels i.e., 0, 9, 18 and 36 mg. The second factor was the color of monochromatic light consisted of 4 levels i.e., white, red, green and blue. Results: The results showed the interaction effects between curcumin and monochromatic light on the liver weight, hepatocytes diameter, DNA and RNA concentrations in the liver cells (p<0.05). Serum estradiol and vitellogenin concentrations in female magelang ducks during sexual maturity prior to laying period ranged from 0.06-0.19 and 0.36-3.46 mg mL–1, respectively. Curcumin supplementation at doses of 18 and 36 mg duck–1 day–1 increased the diameters of F1 follicles by 21.62 and 17.91%, respectively. Conclusion: It is concluded that curcumin supplementation at a dose of 18 mg duck–1 day–1 combined with the use of red or greenlight can improve the biosynthesis capacity of egg yolk protein precursors by liver cells without increasing liver cells proliferation. Moreover, the increased estradiol during vitellogenesis is also necessary in the recruitment of ovarian follicles in establishing the F1 hierarchical follicles.
References
Arukwe, A. and A. Goksoyr, 2003. Eggshell and egg yolk proteins in fish: Hepatic proteins for the next generation: oogenetic, population and evolutionary implications of endocrine disruption. Comp. Hepatol., Vol. 2.
Turker, H. and A. Bozcaarmutlu, 2009. Effect of total isoflavones found in soybean on vitellogenin production in common carp. Kafkas Universitesi Veteriner Fakultesi Dergisi, 15: 561-568.
Challenger, W.O., T.D. Williams, J.K. Christians and F. Vezina, 2001. Follicular development and plasma yolk precursor dynamics through the laying cycle in the european starling (Sturnus vulgaris). Physiol. Biochem. Zool., 74: 356-365.
Hermier, D., G. Guy, S. Guillaumin, S. Davail, J.M. Andre and R. Hoo-Paris, 2003. Differential channelling of liver lipids in relation to susceptibility to hepatic steatosis in two species of ducks. Comp. Biochem. Physiol. Part B: Biochem. Mol. Biol., 135: 663-675.
Tarek, K., M. Mohamed, B. Hassina, B. Omar and I. Messaouda, 2013. Histological changes in liver and pectoral muscles of broiler chickens slaughtered with and without naming of Allah. Int. J. Poult. Sci., 12: 550-552.
Stevens, L., 1991. Egg white proteins. Comp. Biochem. Physiol. Part B: Comp. Biochem., 100: 1-9.
Levi, L., I. Pekarski, E. Gutman, P. Fortina and T. Hyslop et al., 2009. Revealing genes associated with vitellogenesis in the liver of the zebrafish (Danio rerio) by transcriptome profiling. BMC Genomics, Vol. 10.
Rajput, N., M. Naeem, S. Ali, J.F. Zhang, L. Zhang and T. Wang, 2013. The effect of dietary supplementation with the natural carotenoids curcumin and lutein on broiler pigmentation and immunity. Poult. Sci., 92: 1177-1185.
Kasiyati, N. Kusumorini, H. Maheshwari and W. Manalu, 2009. Kadar estrogen dan profil oviduk puyuh (Coturnix coturnix Japonica) setelah pemberian cahaya monokromatik. Anatomi Fisiologi, 17: 1-11.
Kasiyati, N. Kusumorini, H. Maheshwari and W. Manalu, 2010. Fotostimulasi cahaya monokromatik untuk optimasi reproduksi dan karakteristik karkas puyuh (Coturnix coturnix Japonica) masak kelamin. Proceedings of the Prosiding Seminar Nasional: Peranan Teknologi Reproduksi Hewan Dalam Rangka Swasembada Pangan Nasional, October 6-7, 2010, Bogor, pp: 118-122.
Kasiyati, N. Kusumorini, H. Maheshwari and W. Manalu, 2011. Penerapan cahaya monokromatik untuk perbaikan kuantitas telur puyuh. Buletin Anatomi Fisiologi, 19: 1-7.
Bengmark, S., 2006. Curcumin, an atoxic antioxidant and natural NFκB, cyclooxygenase-2, lipooxygenase and inducible nitric oxide synthase inhibitor: A shield against acute and chronic diseases. J. Parenter. Entral Nutr., 30: 45-51.
Prasad, S., A.K. Tyagi and B.B. Aggarwal, 2014. Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: The golden pigment from golden spice. Cancer Res. Treatment, 46: 2-18.
Leeson, S. and J.D. Summers, 2005. Commercial Poultry Nutrition. 3rd Edn., Nottingham University Press, England.
Laemmli, U.K., 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227: 680-685.
Gibbins, A.M.V., F.R. van de Voort and R. Braham, 1981. Comparative study of three different forms of both native and subunit vitellogenin identified in quail plasma. Compar. Biochem. Physiol. Part B: Compar. Biochem., 70: 731-738.
Nash, J.P., B. Davail-Cuisset, S. Bhattacharyya, H.C. Suter, F. Le Menn and D.E. Kirne, 2000. An Enzyme Linked Immunosorbant Assay (ELISA) for testosterone, estradiol and 17,20β-dihydroxy-4-pregenen-3-one using acetylcholinesterase as tracer: Application to measurement of diel patterns in rainbow trout (Oncorhynchus mykiss). Fish Physiol. Biochem., 22: 355-363.
Bancroft, J.D. and M. Gamble, 2008. Theory and Practice of Histological Techniques. Elsevier Health Sciences, United Kingdom, ISBN: 9780443102790, Pages: 725.
Manalu, W. and M.Y. Sumaryadi, 1998. Maternal serum progesterone concentration during gestation and mammary gland growth and development at parturition in Javanese thin-tail ewes carrying a single or multiple fetuses. Small Rumin. Res., 27: 131-136.
SAS., 2002. The SAS System for Windows. Release 9.0, SAS Institute Inc., Cary, NC., USA.
Kasiyati, W. Manalu, Sumiati and D.R. Ekastuti, 2016. Efficacy of curcumin and monochromatic light in improving liver functions of sexually mature magelang ducks. J. Indonesian Trop. Anim. Agric., 41: 153-160.
Saraswati, T.R., W. Manalu, D.R. Ekastuti and N. Kusumorini, 2013. Increased egg production of Japanese quail (Cortunix japonica) by improving liver function through turmeric powder supplementation. Int. J. Poult. Sci., 12: 601-614.
Tata, J.R., 1979. Control by oestrogen of reversible gene expression: The vitellogenin model. J. Steroid Biochem., 11: 361-371.
Skipper, J.K. and T.H. Hamilton, 1977. Regulation by estrogen of the vitellogenin gene. Proc. Nat. Acad. Sci., 74: 2384-2388.
Shapiro, D. and J.M. Taylor, 1982. Steroid hormone regulation of vitellogenin gene expressio. CRC Critical Rev. Biochem., 12: 187-203.
Dewi, C.D., D.R. Ekastuti, A.O. Sudrajat and W. Manalu, 2016. Improved vitellogenesis, gonad development and egg diameter in catfish (Pangasianodon hypophthalmus) supplemented with turmeric (Curcuma longa) powder. Aquaculture Research, (In Press).
Sumpter, J.P. and S. Jobling, 1995. Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment. Environ. Health Perspect., 103: 173-178.
Hache, R.J., S.P. Tam, A. Cochrane, M. Nesheim and R.G. Deeley, 1987. Long-term effects of estrogen on avian liver: Estrogen-inducible switch in expression of nuclear, hormone-binding proteins. Mol. Cell. Biol., 7: 3538-3547.
Wiskocil, R., P. Bensky, W. Dower, R.F. Goldberger, J.I. Gordon and R.G. Deeley, 1980. Coordinate regulation of two estrogen-dependent genes in avian liver. Proc. Nat. Acad. Sci., 77: 4474-4478.
Bachmeier, B.E., V. Mirisola, F. Romeo, L. Generoso and A. Esposito et al., 2010. Reference profile correlation reveals estrogen-like trancriptional activity of curcumin. Cell Physiol. Biochem., 26: 471-482.
Nath, P. and B.I. Sundararaj, 1979. Role of protein and steroid hormones in vitellogenesis in the catfish, Heteropneustes fossilis. Proc. Indian. Natl. Sci. Acad., 45: 491-496.
Baxter, M., N. Joseph, V.R. Osborne and G.Y. Bedecarrats, 2014. Red light is necessary to activate the reproductive axis in chickens independently of the retina of the eye. Poult. Sci., 93: 1289-1297.
Hartwig, H.G. and T. van Veen, 1979. Spectral characteristics of visible radiation penetrating into the brain and stimulating extraretinal photoreceptors. J. Compa. Physiol., 130: 277-282.
Downloads
Published
Issue
Section
License
Copyright (c) 2016 The Author(s)
This work is licensed under a Creative Commons Attribution 4.0 International License.
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
