The Effect of Insulin like Growth Factor Binding Protein 2 Gene on Kampung Chicken Growth Rate
DOI:
https://doi.org/10.3923/ijps.2013.495.500Keywords:
Growth rate, heritability, Kampung chickenAbstract
Insulin-like growth factor binding protein 2 regulates a broad spectrum of biological activities involved in growth, development and differentiation. The current study was designed to investigate the associations of IGFBP2 gene polymorphisms with the variance components and genetic parameters of four weekly intervals of growth rate (0-4, 4-8, 8-12 weeks) of the Kampung chicken that were evaluated with classical models of quantitative genetics. Thirty two females and 16 males Kampung chicken were genotyped with IGFBP2 gene using PCR-RFLP method. Retrieved 3 genotype (CC, CT and TT) and 2 alleles (C and T). The influence of average effect of the C allele was greater than T allele on a 4-8 weeks intervals of growth rate, meanwhile for the males turn into 0-4 and 8-12 weeks interval growth rate. Ratio component additive and dominant deviation to each genotype is always equal for each interval growth rate. Variance component from heterozygote nearly zero when frequency of homozygote nearly equal and ratio variance dominance were opposite to allele frequency. Narrow-sense heritability based on genetic variance component of 0-4, 4-8 and 8-12 weeks interval growth rate for female were 0.01, 0.47 and 0.87 while for male chicken were 0.94, 0.07 and 0.12, respectively. It was concluded that IGFBP 2 gene association with growth rate on 4-8 and 8-12 weeks on females but in males only effect on growth rate on 0-4 weeks.
References
Amills, M., N. Jimenez, D. Villalba, M. Tor and E. Molina et al., 2003. Identification of three single nucleotide polymorphisms in the chicken insulin-like growth factor 1 and 2 genes and their associations with growth and feeding traits. Poult. Sci., 82: 1485-1493.
Bahmanimehr, A., 2012. Selection for economic traits in chickens breeding program according to genetic parameters and correlation between traits. World Applied Sci. J., 20: 1332-1335.
Dana, N., E.H. vander Waaij and J.A.M. van Arendonk, 2011. Genetic and phenotypic parameter estimates for body weights and egg production in Horro chicken of Ethiopia. Trop. Anim. Health Prod., 43: 21-28.
De Smit, L., K. Tona, V. Bruggeman, O. Onagbesan, M. Hassanzadeh, L. Arckens and E. Decuypere, 2005. Comparison of three lines of broilers differing in ascites susceptibility or growth rate. 2. Egg weight loss, gas pressures, embryonic heat production and physiological hormone levels. Poult. Sci., 84: 1446-1452.
Falconer, D.S. and T.F.C. MacKay, 1997. Introduction to Quantitative Genetics. 4th Edn., Longman Publishers, Malaysia.
Griffiths, A.J.F., J.H. Miller, D.T. Suzuki, R.C. Lewontin and W.M. Gelbart, 2000. An Introduction to Genetic Analysis. 7th Edn., W.H. Freeman, New York, USA., ISBN-13: 9780716735205, Pages: 860.
Kaps, M. and W.R. Lamberson, 2004. Biostatistics for Animal Science. CABI Publication, Wallingford, UK., ISBN-13: 9780851998206, Pages: 445.
Kim, J.W., 2010. The endocrine regulation of chicken growth. Asian-Austr. J. Anim. Sci., 23: 1668-1676.
Lei, M., C. Luo, X. Peng, M. Fang and Q. Nie et al., 2007. Polymorphism of growth-correlated genes associated with fatness and muscle fiber traits in chickens. Poult. Sci., 86: 835-842.
Lei, M.M., Q.H. Nie, X. Peng, D.X. Zhang and X.Q. Zhang, 2005. Single nucleotide polymorphisms of the chicken insulin-like factor binding protein 2 gene associated with chicken growth and carcass traits. Poult. Sci., 84: 1191-1198.
Li, Z.H., H. Li, H. Zhang, S.Z. Wang, Q.G. Wang and Y.X. Wang, 2006. Identification of a single nucleotide polymorphism of the insulin-like growth factor binding protein 2 gene and its association with growth and body composition traits in the chicken. J. Anim. Sci., 84: 2902-2906.
Nataamijaya, A.G., 2010. Native chickens' potential development for supporting farmers' welfare improvement. J. Litbang Pertan., 29: 131-138.
Nie, Q., B. Sun, D. Zhang, C. Luo and N.A. Ishag et al., 2005. High diversity of the chicken growth hormone gene and effects on growth and carcass traits. J. Heredity, 96: 698-703.
Prado-Gonzalez, E.A., L. Ramirez-Avila and J.C. Segura-Correa, 2003. Genetic parameters for body weights of Creole chickens from Southeastern Mexico using an animal model. Livestock Research for Rural Development, pp: 15. http://www.lrrd.org/lrrd15/1/prad151.htm.
Riztyan, T. Katano, T. Shimogiri, K. Kawabe and S. Okamoto, 2011. Genetic diversity and population structure of Indonesian native chickens based on single nucleotide polymorphism markers. Poult. Sci., 90: 2471-2478.
Schoen, T.J., K. Mazuruk, R.J. Waldbillig, J. Potts, D.C. Beebe, G.J. Chader and I.R. Rodriguez, 1995. Cloning and characterization of a chick embryo cDNA and gene for IGF-binding protein-2. J. Mol. Endocrinol., 15: 49-59.
Templeton, A.R., 2006. Population Genetics and Microevolutionary Theory. John Willey and Sons Inc., New York, USA., ISBN-13: 9780470047217, Pages: 512.
Toghiani, S., 2012. Quantitative Genetic Application in the Selection Process for Livestock Production. In: Livestock Production, Javed, K. (Ed.). InTech Publishers, New York, USA., pp: 3-33.
Vignal, A., D. Milan, M. SanCristobal and A. Eggen, 2002. A review on SNP and other types of molecular markers and their use in animal genetics. Genet. Select. Evol., 34: 275-305.
Sri-Sudaryati, J.H.P. Sidadolog, Wihandoyo and W.T. Artama, 2010. Identification of single nucleotide polymorphism of gen insuline-like growth factor binding protein 2 on growth of native chicken. Proceedings of 5th International Seminar on Tropical Animal Production: Community Empowerment and Tropical Animal Industry, October 19-22, 2010, Faculty of Animal Science, Universitas Gadjah Mada, Yogyakarta.
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