Ultrastructural Studies of Involuting Bursa and Thymus of Giriraja Birds (Gallus domesticus)


Authors

  • Leena Chandrasekhar Department of Veterinary Anatomy and Histology, Veterinary College, Karnataka Veterinary Animal and Fisheries Science University, 560024, Bangalore, India
  • R.V. Prasad Department of Veterinary Anatomy and Histology, Veterinary College, Karnataka Veterinary Animal and Fisheries Science University, 560024, Bangalore, India
  • K.V. Jamuna Department of Veterinary Anatomy and Histology, Veterinary College, Karnataka Veterinary Animal and Fisheries Science University, 560024, Bangalore, India

DOI:

https://doi.org/10.3923/ijps.2012.397.399

Keywords:

Bursa, involution, thymus, ultrastructure

Abstract

The ultra structural changes of involuting cells of bursa of fabricius and thymus could be classified as nuclear and cytoplasmic changes. Major cytoplasmic changes include arrangement of cytoskeletal filaments in parallel arrays, cytoplasmic membrane blebbing and dilatation of endoplasmic reticulum. Nuclear changes included clumping of chromatin, elongation and appearance of convolutions of the nuclear membrane with karyorrhexis, karyolysis and nucleolar disintegration. There is consequent cell volume reduction, detachment of cell from surroundings, formation of several membrane bound apoptotic bodies and its ingestion by neighboring cells.

References

Luft, J.H., 1961. Improvements in epoxy resin embedding methods. J. Biophys. Biochem. Cytol., 9: 409-414.

Machaca, K. and M.M. Compton, 1993. Analysis of thymic lymphocyte apoptosis using in vitro techniques. Dev. Comparative Immunol., 17: 263-276.

Negoescu, A., P. Lorimier, F. Labat-Moleur , L. Azoti and C. Robert et al., 1997. TUNEL: Improvement and evaluation of the method for In situ apoptotic cell identification. Biochemica, 2: 12-17.

West, N.J., E.D. Courtney, A.P. Poullis and R.J. Leicester, 2009. Apoptosis in the colonic crypt, colorectal adenomata and manipulation by chemoprevention. Cancer Epidemiol. Biomarkers Prev., 18: 1680-1687.

MacLellan, W.R. and M.D. Scheider, 1997. Death by design: Programmed cell death in cardiovascular biology and disease. Circ. Res., 81: 137-144.

Sanchez-Refusta, F., E. Ciriaco, A. Germana, G. Germana and J.A. Vega, 1996. Age-related changes in the medullary reticular epithelial cells of the pigeon bursa of Fabricius. Anat. Rec., 246: 473-480.

Tizard, I.R., 2000. Veterinary Immunology: And Introduction. 6th Edn., W.B. Saunders Company, Philadelphia, ISBN: 9780721682181, pp: 161-162.

O'Donnell McGee, J., P.G. Isaacson and N.A. Wright, 1992. Oxford Textbook of Pathology. Oxford University Press, Oxford, UK., ISBN: 9780192619754, Pages: 2344.

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Published

2012-05-15

Issue

Section

Research Article

How to Cite

Chandrasekhar, L., Prasad, R., & Jamuna, K. (2012). Ultrastructural Studies of Involuting Bursa and Thymus of Giriraja Birds (Gallus domesticus). International Journal of Poultry Science, 11(6), 397–399. https://doi.org/10.3923/ijps.2012.397.399